Clinical and laboratory study
Erythroderma: A clinical and follow-up study of 102 patients, with special emphasis on survival

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Abstract

Background: Erythroderma may result from different causes. There have been no publications on this subject with special emphasis on survival.

Objective: The aim of the study was to determine the cause of the erythroderma and the prognosis of these patients.

Methods: Clinical and follow-up data from 102 patients with erythroderma were analyzed. We estimated survival of patients with erythroderma, from causes other than Se´zary syndrome, mycosis fungoides, or leukemia cutis. The survival was compared with that of an age-matched control group of the general population.

Results: The main cause of erythroderma was exacerbation of a preexisting dermatosis (53%). Drug reactions were rarely the cause (5%). A high proportion of the patients had chronic actinic dermatitis/actinic reticuloid (12%). Survival of men with erythroderma was significantly lower than that of the general population.

Conclusion: Men with erythroderma, from causes other than Se´zary syndrome, mycosis fungoides, or leukemia cutis, have a lower survival than men in the general population.

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