Fast track — Research LettersEfficacy of meningococcal serogroup C conjugate vaccine in teenagers and toddlers in England
References (5)
- et al.
Evaluation of the applied biosystems automated Taqman polymerase chain reaction system for the detection of meningococcal DNA
FEMS Immunol Med Microbiol
(2000) - et al.
Avaliação do efeito protetor de vacina polissacarídica antimeningocícica do grupo C, em crianças de 6 a 36 meses
Rev Inst Adolfo Lutz
(1978)
Cited by (311)
Bacterial Meningitis
2023, Manson's Tropical Diseases, Fourth EditionA half-century of meningococcal vaccines
2021, VaccineInvasive Pneumococcal and Meningococcal Disease
2019, Infectious Disease Clinics of North AmericaCitation Excerpt :The dramatic increase in serogroup C IMD in the United Kingdom in the 1990s prompted development of the monovalent meningococcal C conjugate vaccine.81 After introduction into the vaccination schedule for infants in 1999, there was a significant decrease in meningococcal C disease with vaccine efficacy of 97% in teenagers and 92% in toddlers and evidence of a herd immunity effect.82 Immunization schedules in the United Kingdom and other countries now reflect evidence of improved efficacy in older children, administering 1 dose of MenC vaccine at 1 year followed by a quadrivalent conjugate vaccine (Men ACWY) at 14 years.
Development and pre-clinical evaluation of a synthetic oligosaccharide-protein conjugate vaccine against Neisseria meningitidis serogroup C
2019, VaccineCitation Excerpt :However, PS based meningococcal vaccines are poorly immunogenic in infants, and in addition MenC PS vaccine induces immunologic hyporesponsiveness in adults [1–4]. On the contrary, PS-protein conjugate vaccines are immunogenic in infants and induce long-term protection [1,5–7]. Recent meningitis outbreaks in Africa and an acute shortage of meningococcal C vaccine suggests the need for development of simple, effective and affordable MenC conjugate vaccine [8].
Meningococcal Capsular Group A, C, W, and Y Conjugate Vaccines
2017, Plotkin's Vaccines