Effective short-term diazepam prophylaxis in febrile convulsions†,††
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Cited by (94)
Evaluation and practical management: Approach to simple and complex febrile seizures
2022, Febrile Seizures: New Concepts and ConsequencesThe incidence and prevalence of febrile seizures and febrile status epilepticus
2022, Febrile Seizures: New Concepts and ConsequencesComplex febrile seizures—A systematic review
2017, Disease-a-MonthCitation Excerpt :The author concluded carbamazepine makes the recurrence worse. The efficacy of Diazepam administration during febrile illnesses in prevention of recurrent seizure was also evaluated (class IV).47 One group received short-term prophylaxis for 18 months with rectally administered diazepam whenever the temperature was greater than or equal to 38.5°C.
New guidelines for management of febrile seizures in Japan
2017, Brain and DevelopmentCitation Excerpt :The prophylactic use of diazepam is one of the most important topics in the guidelines. The effectiveness of oral or suppository diazepam during febrile illness for prophylaxis of FS is reported in the literature [36–38]. On the other hand, two thirds of children with first FS do not have recurrence of the FS, and these patients do not need diazepam prophylaxis [32,39].
Rectal diazepam solution is as good as rectal administration of intravenous diazepam in the first-aid cessation of seizures in children with intractable epilepsy
2011, Pediatrics and NeonatologyCitation Excerpt :If given later in the course of the seizure, it was effective in only 57% of patients. When given prophylactically at the time of fever, rectal diazepam was as effective as daily phenobarbital in preventing febrile seizures.22,23 Caregivers can be taught to use rectal diazepam at home.24–27
Treatment of febrile seizures: Historical perspective, current opinions, and potential future directions
2010, Brain and Development
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Supported by Grants 12-2922 and 12-3674 from the Danish Medical Research Council.
- ††
Presented in part at the 15th Epilepsy International Symposium, Washington, D.C., September, 30, 1983.