The distal axis of growth hormone (GH) in nutritional disorders: GH-binding protein, insulin-like growth factor-I (IGF-I), and IGF-I receptors in obesity and anorexia nervosa
References (60)
- et al.
Endocrine function in human obesity
Metabolism
(1981) - et al.
Studies on growth hormone secretion in protein calorie malnutrition
Am J Clin Nutr
(1968) - et al.
The effect of fasting on liver receptors for prolactin and growth hormone
Metabolism
(1981) - et al.
Plasma triglycerides in genetically obese rats
Metabolism
(1969) - et al.
Insulin-like growth factor I receptors on erythrocytes in NIDDM
Diabetes Res Clin Pract
(1989) - et al.
Monoclonal antibodies to receptors for insulin and somatomedin-C
J Biol Chem
(1983) - et al.
Hypothalamic dysfunction in patients with anorexia nervosa
Medicine (Baltimore)
(1974) - et al.
Hypothalamic-endocrine dysfunction in anorexia nervosa
- et al.
Endocrine study of anorexia nervosa
Exp Clin Endocrinol
(1983) - et al.
Differential effects of feeding on the ultradian variation of the growth hormone (GH) response to GH-releasing hormone in normal subjects and patients with obesity and anorexia nervosa
J Clin Endocrinol Metab
(1988)
Effect of cholinergic muscarinic receptor blockade on growth (GH) releasing hormone-(-1–44)-induced GH secretion in anorexia nervosa
J Clin Endocrinol Metab
The effect of the nutritional status and weight changes on hypothalamic function tests in anorexia nervosa
Effects of thyrotrophin-releasing hormone on plasma levels of TSH, FSH, LH and GH in anorexia nervosa
Eur J Clin Invest
Growth hormone release following thyrotrophin-releasing hormone injection into patients with anorexia nervosa
Acta Endocrinol.
Growth hormone and prolactin secretion after growth hormone releasing hormone administration in anorexia nervosa patients, normal controls and tamoxifen-pretreated volunteers
Clin Endocrinol (Oxf)
Somatomedin activity and growth hormone secretion
Acta Paediatr Scand
Growth hormone response in the thinned obese
J Clin Endocrinol Metab
Effect of arginine on serum levels of insulin and growth hormone in obese subjects
Metabolism
Plasma growth hormone response to l-dopa in obese subjects
Metabolism
Impaired growth hormone responses to growth hormone-releasing factor in obesity
N Engl J Med
Metabolic clearance rates of synthetic human growth hormone in lean and obese male rhesus monkeys
J Clin Endocrinol Metab
Growth hormone receptor and serum binding protein: Purification, cloning and expression
Nature
The interrelationship of growth hormone (GH), liver membrane GH receptor, serum GH-binding protein activity and insulin-like growth factor-I (IGF-I) in the male rat
Endocrinology
Absence of serum growth hormone binding protein in patients with growth hormone receptor deficiency (Laron dwarfism)
Alterations of human growth hormone binding by rat liver membranes during hypo- and hyperthyroidism
Endocrinology
The effect of human growth hormone (GH) therapy on GH binding protein in GH deficient children
Acta Endocrinol
Effects of hypo- or hyperthyroidism on growth hormone-binding protein
Clin Endocrinol
A new and convenient assay of growth hormone binding protein activity in human serum
J Clin Endocrinol Metab
Characterization of insulin-like growth factor I receptor on human erythrocytes
J Clin Endocrinol Metab
Estimation of somatomedin-C levels in normal and patients with pituitary disease by radioimmunoassay
J Clin Invest
Cited by (191)
Growth hormone and insulin-like growth factor 1 secretions in eating disorders: Correlations with psychopathological aspects of the disorders
2018, Psychiatry ResearchCitation Excerpt :Furthemore, 24 h hormone production and half life are increased, together with normal or increased responses to stimulation with growth hormone-releasing hormone (GHRH), hexarelin, insulin, apomorphine, L-Dopa, clonidine, and to inhibition with glucose or glucagon (Casanueva et al., 1997; Masuda et al. (1988); Kaye et al., 1998; Coiro et al. (1990); Giusti et al. (1997); Gianotti et al., (1998, 1999, 2000); Douyon and Schteingart (2002); Van Neuwpoort and Drent, 2008. whereas concentrations of GH binding protein (GH-BP), insulin-like growth factor-1 (IGF-1), IGF-1 binding protein (IGF-1-BP), the acid-labile subunits of IGF-BP-3 complex, somatostatin, and hormonal response to acetylcholine agonists are all reduced (Counts et al., 1992; Hochberg et al., 1992; Ghigo et al., 1994; Muller and Rolla, 1996; Mancini et al., 1996; Argente et al., 1998; Stoving et al., 1999; Barrios et al., 2001; Gross et al., 2003; Grinspoon et al., 2003). The reduced synthesis and release of IGF-1 result in impairments of the peripheral effects of GH and negative IGF-1 feedback action on GH secretion (Postel Vinay et al., 1995; Scacchi et al., 2005; Paszynska et al., 2015).
Growth hormone binding protein - Physiological and analytical aspects
2015, Best Practice and Research: Clinical Endocrinology and MetabolismCitation Excerpt :Binding of the placental growth hormone variant (placental GH, GH-V) to the high-affinity GHBP is not different from the binding of pituitary GH [77]. Numerous studies could show a positive correlation between body mass index (BMI) and GHBP levels [68,78–82]. Furthermore, there is a positive correlation of GHBP concentration with (visceral) fat mass, waist circumference, waist-to-hip ratio, insulin secretion, and leptin concentration and a negative correlation with insulin sensitivity and lean body mass [83–85].
Obesity, growth hormone and weight loss
2010, Molecular and Cellular EndocrinologyBioactive insulin-like growth factor-I in obesity
2009, Journal of Clinical Endocrinology and MetabolismRelative growth hormone deficiency and cortisol excess are associated with increased cardiovascular risk markers in obese adolescent girls
2009, Journal of Clinical Endocrinology and MetabolismAndrogens may mediate a relative preservation of IGF-I levels in overweight and obese women despite reduced growth hormone secretion
2008, Journal of Clinical Endocrinology and Metabolism
- 1
Supported by a grant from the Chief Scientist, Israel Ministry of Health, to M.B.H.Y. and T.A.