ReviewMagnesium and its therapeutic uses: A review
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2019, Revue de Medecine InterneCitation Excerpt :International guidelines are heterogeneous regarding magnesium adjunction during AWS, but most of them recommend adjunction only in case of biological deprivation [18,28–30]. When administered orally, therapeutic administration of magnesium salts is particularly safety since oral magnesium supplementation has not been reported to cause elevations of serum magnesium to potentially harmful levels in patients with normal renal function [48]. Since there exist no strict guidelines for use of oral magnesium preparations regarding either dosage or choice of formulation [48], it is suggested to choose a drug already indicated in oral magnesium supplementation with a dosage inside the recommended range and near those used in the previous studies on this topic [18].
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2018, Clinical Nutrition ESPENCitation Excerpt :Several epidemiologic studies have shown that adults and children consuming a western type diet are consuming 30–50% of the RDA for magnesium [47,93,102]. This deficiency appears to be predominantly subclinical and therefore not routinely investigated [11,94,103,104]. Furthermore, the measurement of magnesium in the blood is problematical since it is recognized to be perturbed by the systemic inflammatory response [105], and measurable serum magnesium accounts for only 0.15% of total body magnesium.
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