Abstract
Meningococcal disease (MCD) can present as meningitis, meningitis plus septicaemia or septicaemia alone. This 17-year retrospective study sought to determine if the proportion of cases presenting as septicaemia alone was increasing. Four hundred and forty-nine children with MCD were admitted between 1977 and 1993, 50 children died (11%). The proportion of cases with septicaemia alone increased from 7% in 1977–1985 to 36% in 1990–1993 (P<0.0005). Mortality was highest in children with septicaemia alone (19%). Despite the increase in septicaemia, overall mortality did not alter over the 17 years.
Conclusion
MCD should not be thought of as “meningitis”, since 33% of cases now present as septicaemia alone. Nearly one in five children with septicaemia alone die. Information and publicity about MCD should focus on septicaemia, characterised by a petechial rash, as the life-threatening presentation.
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Abbreviations
- MCD :
-
meningococcal disease
- MM :
-
meningitis alone
- MM+MS :
-
meningitis plus septicaemia
- MS :
-
septicaemia alone
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Riordan, F.A.I., Marzouk, O., Thomson, A.P.J. et al. The changing presentations of meningococcal disease. Eur J Pediatr 154, 472–474 (1995). https://doi.org/10.1007/BF02029358
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DOI: https://doi.org/10.1007/BF02029358