Skip to main content
SpringerLink
Log in

Idiopathic infantile arterial calcification: A surviving patient with renal artery stenosis

  • Originals
  • Published:
Pediatric Radiology Aims and scope Submit manuscript

Abstract

Idiopathic infantile arterial calcification (IIAC) is a rare hereditary, fatal disease. Death occurs usually within the first 28 months of life. IIAC is characterized by calcifications along the internal elastic membrane and proliferation of the intimal layer of muscular arteries. Specific therapy consists of administration of diphosphonates, but its effectiveness has been a matter of controversy. We report a case treated with diphosphonates which has had an unusual outcome.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Moran JJ (1975) Idiopathic arterial calcification of infancy — a clinicopathological study. Pathol Annu 10: 393

    PubMed  Google Scholar 

  2. Vera J, Lucaya J, Garcia Conesa JA, Aso C, Balaguer A (1990) Idiopathic infantile arterial calcification: unusual features. Pediatr Radiol 20: 585–587

    PubMed  Google Scholar 

  3. Meradjii M, De Villeneuve VH, Huber J, De Bruin WC, Pearse RG (1978) Idiopathic infantile arterial calcification in siblings: radiological diagnosis and successful treatment. J Pediatr 92: 401

    PubMed  Google Scholar 

  4. Rosenbaum DM and Blumhagen JD (1986) Sonographic recognition of idiopathic arterial calcification. AJR 146: 249–250

    PubMed  Google Scholar 

  5. Beyer P, Mandard JC, Mandard AM, Klein ML, Meyer A (1971) Une observation d'artériopathie calcification infantile. Presse Méd 51: 2327

    Google Scholar 

  6. Sholler GF, Yu JS, BAle PM, Hawker RE, Celermajer JM, Kozlowski K (1984) Generalized arterial calcification of infancy: three case reports, including spontaneous regression with long term survival. J Pediatr 105: 257

    PubMed  Google Scholar 

  7. Morton R (1978) Idiopathic arterial calcification in infancy. Histopathology 2: 423

    PubMed  Google Scholar 

  8. Thomas P, Chandra M, Kahn E, McVicar M, Naidich J, La Corte M (1990) Idiopathic arterial calcification of infancy: a case with prolonged survival. Pediatr Nephrol 4: 233–235

    PubMed  Google Scholar 

  9. Marrot PK, Newcombe KD, Becroft DMO, Friedlander DH (1984) Idiopathic infantile arterial calcification with survival to adult life. Pediatr Cardiol 5: 119–122

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiology, Hôpital Universitaire des Enfants Reine Fabiola, 15 av J.J. Crocq, B-1020, Brussels, Belgium

    A. Thiaville, A. Smets & N. Perlmutter

  2. Department of Neonatalogy, Hôpital Universitaire des Enfants Reine Fabiola, 15 av J.J. Crocq, B-1020, Brussels, Belgium

    A. Clercx

Authors
  1. A. Thiaville
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. Smets
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. Clercx
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. N. Perlmutter
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Thiaville, A., Smets, A., Clercx, A. et al. Idiopathic infantile arterial calcification: A surviving patient with renal artery stenosis. Pediatr Radiol 24, 506–508 (1994). https://doi.org/10.1007/BF02015014

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02015014

Keywords

Search

Navigation