Abstract
The haemodynamic effects of intermittent high volume venovenous haemofiltration were studied in 13 critically ill patients. The mean negative fluid balance during filtration was 1.2l and the mean duration of treatment 3 h 40 min. The cardiac index fell initially (4.5±0.2 to 3.8±0.2l/min/m2;p<0.05) but then remained stable throughout treatment before returning to baseline at the end of haemofiltration. The mean arterial pressure was unchanged with an increase in the systemic vascular resistance (651±33 to 765±65 dyne·s/cm5;p<0.05) suggesting that vascular responsiveness is maintained during haemofiltration.
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MacKenzie, S.J., Nimmo, G.R., Armstrong, I.R. et al. The haemodynamic effects of intermittent haemofiltration in critically ill patients. Intensive Care Med 17, 346–349 (1991). https://doi.org/10.1007/BF01716194
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DOI: https://doi.org/10.1007/BF01716194