Abstract
Children with central precocious puberty have pituitary gland size comparable to that of pubertal children (pituitary gland height 6.1 ± 1.1 mm). We present of two sisters with precocious puberty and a pituitary gland height of more than 1 cm. On contrast enhanced MRI, there was homogeneous enhancement of the pituitary gland. There was no increase in pituitary gland size during the follow-up period (6 years and 2 years). These cases are reported for their rarity.
Similar content being viewed by others
References
Wenier SN, Rzezotarskli MS, Droege RT, et al (1985) Measurement of pituitary gland height with MR imaging. Am J Neuroradiol 6: 717–722
Gonzalez JG, Elizondo G, Salvidar D, et al (1988) Pituitary gland growth during normal pregnancy: an in vivo study using magnetic resonance imaging. Am J Med 85: 217–220
Sheurie SN, Doraiswamy PM, Husain MM, et al (1990) In vivo assessment of pituitary gland volume with magnetic resonance imaging: the effect of age. J Clin Endocrinol Metab 71: 505–508
Hayakawa K, Konishi Y, Matsuda T, et al (1989) Development and aging of brain midline structures: assessment with MR imaging. Radiology 172: 172–177
Perignon F, Brauner R, Arguropoulou M, et al (1992) Precocious puberty in girls: pituitary height as an index of hypothalamopituitary activation. J Clin Endocrinol Metab 75:1170–1172
Pescovitz OH, Hench KD, Barnes KM, et al (1988) Premature thelarche and central precocious puberty. The relationship between clinical presentation and the gonadotropin response to LHRH. J Clin Endocrinol Metab 67: 447–479
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Gupta, R., Ammini, A.C. Precocious puberty with pituitary gland hyperplasia: Two cases in one family. Pediatr Radiol 26, 418–420 (1996). https://doi.org/10.1007/BF01387318
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01387318