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Prevalence of infantile autism in four French regions

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Summary

A survey conducted in four French regions identified a sample of 154 autistic children born in the birth cohorts 1972 and 1976. Their mean ages were respectively 6.9 and 5.5 years when their handicaps were registered to local administrative services. The overall prevalence estimate is 4.9/10,000, with little difference between the two cohorts. The boy/girl sex ratio is 2.1∶1, and more than two thirds are mentally retarded. The SES distribution does not deviate from census data. An elevated incidence of epilepsy is found (22%), with higher rates among the most retarded subjects and those with perinatal antecedents. Otherwise, relatively few autistic subjects were reported to have a clearcut medical disorder known for its association with autism.

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References

  • American Psychiatric Association (1987) Diagnostic and statistical manual of mental disorders-DSM-III-R, 3rd rev. edn American Psychiatric Association Washington

    Google Scholar 

  • Aussilloux C, Collery F, Roy J (1989) Epidémiologie de l'autisme infantile dans le département de l'Hérault. Rev Fr Psychiatrie 7: 24–28

    Google Scholar 

  • Bohman M, Bohman IL, Björck PO, Sjöhlm E (1983) Childhood psychosis in a northern Swedish county: some preliminary findings from an epidemiological survey. In: Schmidt MH, Remschmidt H (eds) Epidemiological approaches in child psychiatry. Thieme Stuttgart, pp 164–173

    Google Scholar 

  • Bolton P, Rutter M (1990) Genetic influences in autism. Int Rev Psychiatry 2: 65–78

    Google Scholar 

  • Brask BH (1972) A prevalence investigation of childhood psychoses. In: Nordic Symposium on the Care of Psychotic Children Barnepsychiatrist Forenin, Oslo

  • Bréart G, du Mazaubrun C, Maillard F (1988) Evaluation à long terme des actions périnatales et évolution récente de la prématurité. Chercher pour agir-Recherche d'aujourd'hui, Médecine d'aujourd'hui et de demain. 2éme Colloque CNAMTS-INSERM 187: 169–176

    Google Scholar 

  • Bryson SE, Clark BS, Smith IM (1988) First report of a canadian epidemiological study of autistic syndromes. J Child Psychol Psychiatry 4: 433–445

    Google Scholar 

  • Burd L, Fisher W, Kerbeshan J (1987) A prevalence study of pervasive developmental disorders in North Dakota. J Am Acad Child and Adolesc Psychiatry 26: 700–703

    Google Scholar 

  • Cialdella Ph, Mamelle N (1989) An epidemiological study of infantile autism in a French department. J Child Psychol Psychiatry 30: 165–175

    Google Scholar 

  • Creak M (1963) Childhood psychosis: a review of 100 cases. Br J Psychiatry 109: 84–89

    Google Scholar 

  • Deykin EY, MacMahon B (1979) The incidence of seizures among children with autistic symptoms. Am J Psychiatry 136: 10 1310–1312

    Google Scholar 

  • Deykin EY, MacMahon B (1980) Pregnancy, delivery and neonatal complications among autistic children. Am J Dis Child 134: 860–864

    Google Scholar 

  • Finegan JA, Quarrington B (1979) Pre-, peri-, and neonatal factors and infantile autism. J Child Psychol Psychiatry 20: 119–128

    Google Scholar 

  • Folstein S, Rutter M (1977) Infantile autism: a genetic study of 21 twin pairs. J Child Psychol Psychiatry 18: 297–321

    Google Scholar 

  • Fombonne E (1992a) Etudes épidémiologiques de l'autisme infantile. In: Lebovici S, Diatkine R, Soulé M (eds) Traité de Psychiatrie de l'enfant et de l'adolescent, 2ème édn, PUF, Paris (in press)

    Google Scholar 

  • Fombonne E (1992b) Diagnostic assessment in a sample of autistic and developmentally delayed adolescents. J Autism Dev Disord (in press)

  • Fombonne E, Achard S (1991) Une étude multicentrique sur l'autisme et les psychoses infantiles. Handicaps et inadaptations. Les cahiers du CTNERHI, Nos. 55-56, pp 7–19

  • Gillberg C (1984) Infantile autism and other childhood psychoses in a Swedish region: epidemiological aspects. J Child Psychol Psychiatry 25: 35–43

    Google Scholar 

  • Gillberg C, Gillberg IC (1983) Infantile autism: a total population study of reduced optimality in the pre-, peri-and neonatal period. J Autism Dev Disord 13: 153–155

    Google Scholar 

  • Gillberg C, Forsell C (1984) Childhood psychosis and neurofibromatosis-more than a coincidence. J Autism Dev Disord 13: 1–8

    Google Scholar 

  • Goodman R (1990) Are perinatal complications causes or consequences of autism? J Child Psychol Psychiatry 31: 809–812

    Google Scholar 

  • Hoshino Y, Kumashiro H, Yashima Y, Tachibana R, Watanabe M (1982) The epidemiological study of autism in Fukushima-ken. Folia Psychiatr Neurol Japon 36: 115–124

    Google Scholar 

  • Kanner L (1943) Autistic disturbances of affective contact. Nervous Child 2: 217–250

    Google Scholar 

  • Knobloch H, Pasamanick B (1975) Some etiologic and prognostic factors in early infantile autism and psychosis. Pediatrics 2: 182–191

    Google Scholar 

  • Kolvin I, Ounsted C, Roth M (1971) Studies in the childhood psychoses. V. Cerebral dysfunction and childhood psychoses. Br J Psychiatry 118: 407–414

    Google Scholar 

  • Le Couteur A, Rutter M, Lord C, Rios P, Robertson S, Holdgrafer M, MacLennan J (1989) Autism diagnostic interview: a standardized investigator-based instrument. J Autism Dev Disord 19: 363–387

    Google Scholar 

  • Lotter V (1966) Epidemiology of autistic conditions in young children: I. Prevalence. Soc Psychiatry 1: 124–137

    Google Scholar 

  • Mason-Brothers A, Ritvo ER, Pingree C, Petersen PB, Jenson WR, McMahon WM, Freeman BJ, Jorde LB, Spencer MJ, Mo A, Ritvo A (1990) The UCLA-University of Utah epidemiologic survey of autism: prenatal, perinatal, and postnatal factors. Pediatrics 86: 514–519

    Google Scholar 

  • McCarthy P, Fitzgerald M, Smith MA (1984) Prevalence of childhood autism in Ireland. Ir Med J 77: 129–130

    Google Scholar 

  • Misès R, Fortineau J, Jeammet Ph, Lang J-L, Mazet, Ph, Plantade A, Quémada N (1988) Classification Française des troubles mentaux de l'enfant et de l'adolescent. Psychiatr Enfant 31: 67–134

    Google Scholar 

  • Olsson I, Steffenburg S, Gillberg C (1988) Epilepsy in autism and autisticlike conditions. Arch Neurol 45: 666–668

    Google Scholar 

  • Rantakallio P, von Wendt (1985) Risk factors for mental retardation. Arch Dis Child 60: 946–952

    Google Scholar 

  • Ritvo ER, Freeman BJ, Pingree C, Mason-Brothers A Jorde L, Jenson WR, McMahon WM, Petersen PB, Mo A, Ritvo A (1989) The UCLA-University of Utah epidemiologic survey of autism, prevalence. Am J Psychiatry 146: 194–199

    Google Scholar 

  • Rumeau-Rouquette C, du Mazaubrun C, Rabarison Y (1984) Naître en France: 10 ans d'évolution 1972–1981. Doin/Editions INSERM, Paris

    Google Scholar 

  • Rumeau-Rouquette C, du Mazaubrun C, Mlika A, Dequae L (1991) Motor handicapped children: comparison of three birth cohorts 1972, 1976 and 1981 among 4 French geographical areas (submitted)

  • Rutter M (1970) Autistic children: infancy to adulthood. Semin Psychiatry 2: 435–450

    Google Scholar 

  • Rutter M (1983) Cognitive deficits in the pathogenesis of autism. J Child Psychol Psychiatry 24: 513–531

    Google Scholar 

  • Rutter M (1991) Autism as a genetic disorder. In: McGuffin P, Murray RM (eds) The new genetics of mental illness. Butterworth-Heinemann, Oxford

    Google Scholar 

  • Schopler E, Andrews CE, Strupp K (1979) Do autistic children come from upper-middle-class parents? J Autism Dev Disord 9: 139–151

    Google Scholar 

  • Smalley SL, Asarnow RE, Spence MA (1988) Autism and genetics. A decade of research. Arch Gen Psychiatry 45: 953–961

    Google Scholar 

  • Steffenburg S, Gillberg C (1986) Autism and autistic-like conditions in Swedish rural and urban areas: a population study. Br J Psychiatry 149: 81–87

    Google Scholar 

  • Steffenburg S, Gillberg C, Hellgren L, Andersson L, Gillberg C, Jakobsson G, Bohman M (1989) A twin study of autism in Denmark, Finland, Iceland, Norway and Sweden. J Child Psychol Psychiatry 3: 405–416

    Google Scholar 

  • Steinhausen H-C, Göbel D, Breinlinger M, Wohlloben B (1986) A community survey of infantile autism. J Am Acad Child Adolesc Psychiatry 25: 2 186–189

    Google Scholar 

  • Sugiyama T, Abe T (1989) The prevalence of autism in Nagoya, Japan: a total population study. J Autism Dev Disord 19: 87–96

    Google Scholar 

  • Tanoue Y, Oda S, Asano F, Kawashima K (1988) Epidemiology of infantile autism in Southern Ibaraki, Japan: differences in prevalence in birth cohorts. J Autism Dev Disord 18: 155–166

    Google Scholar 

  • Torrey EF, Hersh SP, McCabe KD (1975) Early childhood psychosis and bleeding during pregnancy. J Autism Child Schizophr 5: 287–297

    Google Scholar 

  • Treffert DA (1970) Epidemiology of infantile autism. Arch Gen Psychiatry 22: 431–438

    Google Scholar 

  • Tsai L, Stewart MA, Faust M, Shook S (1982) Social class distribution of fathers of children enrolled in the Iowa autism program. J Autism Dev Disord 12: 211–221

    Google Scholar 

  • Volkmar FR, Nelson DS (1990) Seizure disorders in autism. J Am Acad Child Adolesc Psychiatry 1: 127–129

    Google Scholar 

  • Wing I (1980) Childhood autism and social class: a question of selection? Br J Psychiatry 137: 410–417

    Google Scholar 

  • Wing L, Yeates SR, Brierly LM, Gould J (1976) The prevalence of early childhood autism: comparison of administrative and epidemiological studies. Psychol Med 6: 89–100

    Google Scholar 

  • Wing L, Gould J (1979) Severe impairments of social interactions and associated abnormalities in children: epidemiology and classification. J Autism Dev Disord 9: 11–29

    Google Scholar 

  • World Health Organization (1988) ICD-101988 draft of chapter V categories F00-F99: mental, behavioural and developmental disorders. Clinical description and diagnostic guidelines (MNH/MEP/87.1, revision 2). World Health Organization, Geneva

    Google Scholar 

  • Zahner GEP, Pauls DL (1987) Epidemiological surveys of infantile autism. In: Cohen DJ, Donnellan AM, Paul R (eds) Handbook of autism and pervasive and developmental disorders. Wiley, New-York pp 199–207

    Google Scholar 

Download references

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Authors and Affiliations

  1. Centre Alfred Binet, INSERM, 76, Avenue Edison, F-75013, Paris, France

    E. Fombonne

  2. Unité 149, INSERM, Paris, France

    C. du Mazaubrun

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  1. E. Fombonne
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  2. C. du Mazaubrun
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Fombonne, E., du Mazaubrun, C. Prevalence of infantile autism in four French regions. Soc Psychiatry Psychiatr Epidemiol 27, 203–210 (1992). https://doi.org/10.1007/BF00789007

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