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Controlled fall in natremia in hypertonic dehydration: Possible avoidance of rehydration seizures

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Abstract

This prospective study comprises 40 infants with severe hypernatremic dehydration due to gastroenteritis. During the first 24 h, natremia was closely monitored and infusion rates were adjusted so as to keep the rate of fall in natremia below 0.5 mEq/l/h. This could be achieved by giving a 70 mEq/l Na solution at the rate of 120 ml/kg/24 h. Rehydration was uneventful in all cases, and no convulsions were observed.

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Authors and Affiliations

  1. Intensive Care Unit, Department of Pediatrics, Brussels, Belgium

    A. Kahn & D. Blum

  2. School of Medicine, Free University of Brussels, Brussels, Belgium

    G. Casimir

  3. Laboratory of Pathophysiology, Free University of Brussels, Brussels, Belgium

    E. Brachet

Authors
  1. A. Kahn
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  2. D. Blum
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  3. G. Casimir
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  4. E. Brachet
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Kahn, A., Blum, D., Casimir, G. et al. Controlled fall in natremia in hypertonic dehydration: Possible avoidance of rehydration seizures. Eur J Pediatr 135, 293–296 (1981). https://doi.org/10.1007/BF00442106

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  • DOI: https://doi.org/10.1007/BF00442106

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