Associations of physical activity at age 11 years with chronic disabling fatigue (CDF) at age 16 years
| Raw data (n=3907) | Imputed data (n=13 978)* | ||
| Total physical activity† | Unadjusted OR | 0.87 (0.72, 1.04) | 0.88 (0.74, 1.05) |
| Partially adjusted OR‡ | 0.91 (0.76, 1.10) | 0.91 (0.76, 1.09) | |
| Fully adjusted OR§ | – | 0.94 (0.77, 1.15) | |
| Fully adjusted mean difference (counts/min)§ | −14.7 (−70.8, 41.4) | ||
| Moderate-to-vigorous physical activity¶ | Unadjusted OR | 0.89 (0.76, 1.06) | 0.90 (0.78, 1.04) |
| Partially adjusted OR‡ | 0.95 (0.80, 1.13) | 0.94 (0.81, 1.09) | |
| Fully adjusted OR§ | – | 0.96 (0.82, 1.13) | |
| Fully adjusted mean difference (min/day)§ | −0.82 (−5.48, 3.85) | ||
| Sedentary time** | Unadjusted OR | 1.20 (0.94, 1.52) | 1.23 (0.97, 1.56) |
| Partially adjusted OR‡ | 1.17 (0.92, 1.49) | 1.22 (0.96, 1.54) | |
| Fully adjusted OR§ | – | 1.16 (0.89, 1.51) | |
| Fully adjusted mean difference (min/day)§ | 12.6 (−9.76, 35.0) | ||
*Variables for the multiple imputation (50 imputations) were as follows: CDF at 13 and 16 years; sex; nighttime sleep duration at 7 and 9 years; body mass index (BMI) at 7 and 9 years; child mood at 9 years (Short Moods and Feelings Questionnaire score); maternal depression at 6 years (Edinburgh Postnatal Depression Scale); maternal anxiety at 6 years (Crown-Crisp Experiential Index); mean test score for English, Mathematics and Science at 11 years (Key Stage 2 tests); maternal life events score (antenatal); self-esteem at 8 years (Global Self Worth subscale from Harter’s Self Perception Profile for Children); Avon Longitudinal Study of Parents and Children family adversity index (antenatal); family adversity index at 8–10 years; life difficulties, hyperactivity and internalising behaviour at 11 years (Strengths and Difficulties Questionnaire); screen time at 6 years; special school arrangements for emotional/behavioural problems at 7 years; conduct problems at 8 years; duration of breastfeeding; family income at 4 years; maternal childhood socioeconomic status; maternal education; maternal age at birth of child; maternal psychopathology at 8–10 years; experienced bullying at 8 years; days spent outdoors at 8 years; poor concentration at school at 7 years; maternal and paternal BMI at 8 years; internalising behaviour at 4 years (Strengths and Difficulties Questionnaire); early puberty; dietary patterns at 3 and 10 years.
†For total physical activity, change is per 100 counts/min increase in mean total physical activity for the whole week
‡Adjusted for sex and family adversity index (antenatal).
§Adjusted for sex; family adversity index (antenatal); BMI at 7 and 9 years; maternal depression at 6 years; maternal anxiety at 6 years; internalising behaviour at 4 and 11 years; self-esteem at 8 years; child mood at 9 years; early puberty; Key Stage 2 test scores; duration of breastfeeding; family income at 4 years; screen time at 6 years; maternal childhood socioeconomic status; maternal life events score (antenatal); nighttime sleep duration at 8 years; conduct problems at 8 years; dietary patterns at 10 years.
¶For moderate-to-vigorous physical activity, change is per 15 min increase (threshold ≥3500 counts/min).
**For sedentary time, change is per hour increase.