Table 4

MI and complete case analysis of total HC+LP costs and QALYs and NMB (£20 k) at 6 and 12 months; by treatment group, all adjusted for baseline value, age, sex, baseline SCAS and baseline VAS

SMCSMC plus LPIncremental difference
Mean(SE)nMean(SE)n(95% CI)n
6-month complete case
 Total cost (£)942(89)131563(127)21621 (323 to 919)34
 QALYs0.252(0.021)220.259(0.016)320.008 (−0.057 to 0.073)34
 NMB at £20 000 per QALY4225(578)133762(461)21−464 (−1852 to 925)34
6-month imputed
 Total cost (£)1123(66)491517(54)51394 (236 to 553)100
 QALYs0.247(0.015)490.274(0.014)510.026 (−0.015 to 0.068)100
 NMB at £20 000 per QALY3819(328)493954(276)51135 (−733 to 1003)100
12-month complete case
 Total cost (£)1369(160)111814(211)16445 (−57 to 947)27
 QALYs0.551(0.039)210.597(0.032)300.080 (−0.064 to 0.225)27
 NMB at £20 000 per QALY9454(1202)1110 615(1113)161161 (−1966 to 4289)27
12-month imputed
 Total cost (£)1612(84)492002(67)51390 (189 to 591)100
 QALYs0.533(0.025)490.628(0.021)510.095 (0.030 to 0.160)100
 NMB at £20 000 per QALY9042(521)4910 551(427)511508 (148 to 2869)100
  • HC, health care; LP, Lightning Process; MI, multiple imputation; NMB, net monetary benefit; QALY, quality-adjusted life years; SCAS, Spence Children’s Anxiety Scale; SMC, specialist medical care; VAS, Visual Analogue Scale.