Multivariable results from imputed data set (N=12 996)
| Unadjusted | Adjusted 1* | Adjusted 2† | Adjusted 3‡ | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Measure (non-reference group) | Age outcome (years) | Age at measure (months) | OR | 95% CI | OR | 95% CI | OR | 95% CI | OR | 95% CI | p Value |
| Gender (male) | 0–2 | Birth | 1.34 | 1.19 to 1.50 | 1.32 | 1.18 to 1.48 | 1.33 | 1.18 to 1.49 | 1.32 | 1.18 to 1.49 | <0.001 |
| Gross motor score | 0–2 | 6 | 1.03 | 1.02 to 1.04 | 1.03 | 1.02 to 1.04 | 1.03 | 1.02 to 1.04 | 1.03 | 1.02 to 1.03 | <0.001 |
| Fine motor score | 0–2 | 18 | 0.98 | 0.96 to 1.00 | 0.98 | 0.96 to 0.99 | 0.98 | 0.96 to 1.00 | 0.99 | 0.97 to 1.01 | 0.13 |
| Gender (male) | 2–4.5 | Birth | 1.11 | 0.98 to 1.27 | 1.10 | 0.97 to 1.26 | 1.10 | 0.97 to 1.26 | 1.10 | 0.97 to 1.26 | 0.15 |
| Gross motor score | 2–4.5 | 6 | 1.01 | 1.00 to 1.02 | 1.01 | 1.00 to 1.02 | 1.01 | 1.00 to 1.02 | 1.01 | 1.00 to 1.02 | 0.11 |
| Fine motor score | 2–4.5 | 18 | 0.98 | 0.96 to 1.01 | 0.98 | 0.96 to 1.00 | 0.98 | 0.96 to 1.00 | 0.98 | 0.96 to 1.01 | 0.16 |
| Temper tantrums (often) | 2–4.5 | 18 | 1.26 | 0.99 to 1.61 | 1.26 | 0.99 to 1.60 | 1.27 | 0.99 to 1.61 | 1.16 | 0.91 to 1.48 | 0.23 |
| Gender (male) | 5–11 | Birth | 0.78 | 0.64 to 0.95 | 0.78 | 0.64 to 0.95 | 0.78 | 0.64 to 0.95 | 0.78 | 0.64 to 0.95 | 0.02 |
| Gross motor score | 5–11 | 42 | 0.98 | 0.95 to 1.01 | 0.98 | 0.95 to 1.00 | 0.98 | 0.95 to 1.01 | 0.98 | 0.95 to 1.01 | 0.11 |
| Fine motor score | 5–11 | 42 | 1.00 | 0.98 to 1.03 | 1.02 | 1.00 to 1.04 | 1.02 | 1.00 to 1.04 | 1.02 | 1.00 to 1.04 | 0.05 |
| Temper tantrums (often) | 5–11 | 42 | 1.60 | 1.20 to 2.14 | 1.43 | 1.06 to 1.93 | 1.44 | 1.07 to 1.95 | 1.41 | 1.04 to 1.92 | 0.03 |
| Hyperactivity (abnormal) | 5–11 | 47 | 1.36 | 1.11 to 1.67 | 1.25 | 1.01 to 1.54 | 1.26 | 1.02 to 1.55 | 1.24 | 1.01 to 1.54 | 0.04 |
| Conduct problems (abnormal) | 5–11 | 47 | 1.40 | 1.16 to 1.69 | 1.24 | 1.01 to 1.54 | 1.23 | 0.99 to 1.53 | 1.20 | 0.96 to 1.50 | 0.10 |
| Coordination problems (yes) | 5–11 | 54 | 1.86 | 1.31 to 2.62 | 1.70 | 1.22 to 2.37 | 1.71 | 1.23 to 2.38 | 1.69 | 1.21 to 2.35 | 0.002 |
| Handedness (left/mixed) | 5–11 | 42 | 0.95 | 0.78 to 1.16 | 0.93 | 0.75 to 1.15 | 0.94 | 0.76 to 1.16 | 0.93 | 0.76 to 1.15 | 0.51 |
Full model 0–2 years, OR (95% CI) for confounders; maternal education (degree): 1.34 (1.14 to 1.58), maternal parenting score (worst decile): 1.19 (1.00 to 1.41), marital status (never married): 1.38 (1.20 to 1.60), FAI: 1.11 (1.07 to 1.15), IMD (worst quintile): 1.09 (0.91 to 1.31).
Full model 2–4.5 years, OR (95% CI) for confounders; maternal education (degree): 1.35 (1.12 to 1.62), maternal parenting score (worst decile): 0.89 (0.69 to 1.15), marital status (never married): 1.45 (1.22 to 1.72), FAI: 1.06 (1.02 to 1.10), IMD (worst quintile): 1.08 (0.86 to 1.35).
Full model 5–11 years, OR (95% CI) for confounders: maternal education (degree): 1.36 (1.12 to 1.65), maternal parenting score (worst decile): 1.26 (0.99 to 1.60), marital status (never married): 1.06 (0.83 to 1.34), FAI: 1.05 (1.00 to 1.11), IMD (worst quintile): 0.98 (0.73 to 1.30).
Motor scores are entered as continuous variables.
*Adjusted 1: all child factors.
†Adjusted 2: adjusted 1 + maternal education, maternal parenting score.
‡Adjusted 3: adjusted 2 + marital status, FAI and IMD. p Values reported for adjustment 3 only.
FAI, Family Adversity Index; IMD, Index of Multiple Deprivation.