Baseline characteristics by allocation among 4184 Danish mothers in The Danish Calmette Study
| BCG (N=2095) n (%*) (NA) | Control (N=2089) n (%) (NA) | |
|---|---|---|
| Male sex† | 1092 (52.1) (0) | 1104 (52.9) (0) |
| Prematurity (GA<37 weeks) | 61 (2.9) (0) | 60 (2.9) (0) |
| Randomisation site | (0) | (0) |
| Rigshospitalet | 751 (35.9) | 780 (37.3) |
| Hvidovre | 730 (34.8) | 719 (34.4) |
| Kolding | 614 (29.3) | 590 (28.4) |
| Caesarean section | 411 (19.6) (0) | 442 (21.2) (0) |
| Antibiotics during delivery‡ | 333 (15.9) (0) | 358 (17.1) (0) |
| Singletons | 2061 (98.4) (0) | 2046 (97.9) (0) |
| Twins | 34 (1.6) | 42 (2.0) |
| Triplets | 0 | 1 (0.0) |
| Birth weight in grams (mean±SD) | 3519±493 (0) | 3523±494 (0) |
| Child <1 day of age at randomisation | 1006 (48.0) (0) | 1000 (47.9) (0) |
| Maternal age in years at birth (mean±SD) | 32.0±4.6 (0) | 31.9±4.4 (0) |
| ≥1 parent of ethnicity other than Danish | 376 (18.1) (14) | 458 (22.1) (15) |
| Maternal education | (7) | (6) |
| No higher education | 460 (22.0) | 435 (20.9) |
| Short/medium higher education | 935 (44.8) | 939 (45.1) |
| Long higher education | 693 (33.2) | 709 (34.0) |
| Parents living together | 1984 (94.9) (4) | 1984 (95.0) (0) |
| Mother BCG vaccinated | 364 (17.6) (27) | 353 (17.2) (41) |
| ≥1 older sibling | 887 (42.4) (1) | 843 (40.4) (2) |
| Atopic disposition§ | ||
| Maternal atopic disease | 839 (41.6) (80) | 809 (40.3) (83) |
| Paternal atopic disease | 717 (38.2) (217) | 708 (37.7) (209) |
| Parental atopic disease | 1265 (65.7) (168) | 1243 (64.1) (151) |
| Siblings with atopic disease | 275 (13.3) (30) | 252 (12.2) (23) |
| Smoking during pregnancy | ||
| Maternal | 203 (9.7) (1) | 212 (10.2) (1) |
| Paternal | 388 (18.9) (38) | 458 (22.2) (31) |
*Percentage among families where the information was available.
†The sex of the first child in multiple births.
‡Antibiotics to the mother during elective caesarean section were administered after disconnection of the umbilical cord at the Kolding site and before the umbilical cord was disconnected at Rigshospitalet and Hvidovre sites.
§Atopic disposition defined as physician-diagnosed atopic eczema, asthma, allergic rhinoconjunctivitis or food allergy.
GA, gestational age; NA, not available (number of families without information on the specified variable).