Table 1

Average time in key glycaemic ranges

 Time of dayInsulin administration
 OverallDaytime (6:00–22:00)*Night-time (22:00–6:00)†CSIIMDI
n (participants)8888875038
Sensor glucose, mmol/L
 Mean (SD)9.7 (2.0)9.9 (2.1)9.2 (2.4)9.8 (2.0)9.6 (1.9)
Time in range, hypoglycaemia and hyperglycaemia, hours per day (*per day=16-hour period; †per day=8-hour period)
 3.9–10 mmol/Lmean (SD)12.1 (3.7)8.1 (2.6)4.1 (1.5)12.1 (3.6)12.2 (3.8)
min, max3.6, 21.02.7, 14.30.8, 7.74.2, 21.03.6, 20.0
 <3.9 mmol/Lmean (SD)2.2 (2.2)1.2 (1.3)1.0 (1.0)2.0 (1.6)2.6 (2.8)
min, max0.0, 13.50.0, 9.00.0, 5.70.1, 6.50.0, 13.5
 <3.0 mmol/Lmean (SD)0.9 (1.6)0.4 (0.9)0.5 (0.7)0.7 (0.9)1.3 (2.2)
min, max0.0, 10.50.0, 7.00.0, 4.80.0, 3.40.0, 10.5
 >10.0 mmol/Lmean (SD)9.6 (4.2)6.7 (2.9)2.9 (1.8)9.9 (4.4)9.2 (3.9)
min, max0.0, 19.50.0, 13.10.0, 7.20.4, 19.50.0, 15.4
 >13.3 mmol/Lmean (SD)5.2 (3.4)3.8 (2.5)1.5 (1.3)5.3 (3.5)5.1 (3.3)
min, max0.0, 14.10.0, 10.20.0, 5.30.0, 14.10.0, 11.6
Frequency of hypoglycaemic and hyperglycaemic events per day (24 hours)
 <3.9 mmol/Lmean (SD)1.3 (1.0)1.0 (0.8)0.5 (0.4)1.2 (0.9)1.4 (1.0)
 <3.0 mmol/Lmean (SD)0.6 (0.8)0.4 (0.6)0.3 (0.3)0.5 (0.4)0.7 (1.1)
 >10.0 mmol/Lmean (SD)2.6 (0.8)2.3 (0.7)0.9 (0.5)2.7 (0.8)2.6 (0.8)
 >13.3 mmol/Lmean (SD)1.8 (0.8)1.5 (0.7)0.6 (0.4)1.8 (0.8)1.8 (0.9)
Overall glucose variability
 SD, mmol/L4.5 (1.1)4.5 (1.1)4.0 (1.1)4.4 (0.9)4.6 (1.2)
 Coefficient of variation (subject level), %46.5 (7.8)45.7 (8.0)43.6 (9.6)45.2 (7.7)48.2 (8.1)
  • CSII, continuous subcutaneous insulin infusion; MDI, multiple daily injection.