Table 4

Multiple linear regressions of factors explaining variation in psychomotor scores at preschool age

Model 1 (analysis restricted to complete data)
 Total motor scaleObjective motor scaleSubjective motor scale
R2=13% (N=275)p ValueR2=13% (N=272)p ValueR2=10% (N=283)p Value
b (95% CI)b (95% CI)b (95% CI)
TSH (mIU/L)0.04 (−0.01 to 0.09)0.1030.02 (−0.02 to 0.07)0.2550.03 (−0.01 to 0.08)0.107
Gender<0.001<0.001<0.001
 MaleRefRefRef
 Female0.61 (0.36 to 0.87)0.46 (0.21 to 0.71)0.59 (0.34 to 0.83)
Age at testing (year)−0.41 (−0.66 to −0.15)0.002−0.33 (−0.59 to −0.07)0.013−0.27 (−0.51 to −0.04)0.022
Parity−0.17 (−0.31 to −0.03)0.016−0.23 (−0.36 to −0.91)0.001*
Height at testing (cm)*−0.01 (−0.03 to 0.00)0.055*
Model 2 (with multiple imputation of missing values)
 Total motor scaleObjective motor scaleSubjective motor scale
N=284 p ValueN=284 p ValueN=284 p Value
b (95% CI)b (95% CI)b (95% CI)
TSH (mIU/L)0.03 (−0.02 to 0.08)0.2350.02 (−0.03 to 0.06)0.4900.04 (0.01 to 0.10)0.108
Gender<0.001<0.001<0.001
 MaleRefRefRef
 Female0.58 (0.33 to –0.83)0.44 (0.19 to 0.68)0.59 (0.35 to 0.82)
Age at testing (year)−0.41 (−0.66 to −0.16)0.001−0.35 (−0.60 to −0.10)0.007−0.28 (−0.51 to −0.4)0.022
Parity−0.17 (−0.31, to −0.03)0.018−0.21 (−0.35 to −0.07)0.003*
Height at testing (cm)*−0.01 (−0.03 to 0.01)0.077*

  • PsychoTSH study, Belgium, 2008–2014.

  • Significant associations (p values <0.05) are marked in bold.

  • *Variable not included in the multivariable model.

  • N, number of subjects; TSH, thyroid stimulating hormone.