Prevalence of pregnancies with an NTD and proportion of NTD pregnancies resulting in a termination of pregnancy by register
| Register | Years of notification to EUROCAT | Number of pregnancies with an NTD | Prevalence of pregnancies with an NTD per 1000 births (95% CI) | Proportion of pregnancies (%) with an NTD resulting in a termination of pregnancy (95% CI) |
|---|---|---|---|---|
| South West England | 2005–2012 | 446 | 1.1 (1.0 to 1.2) | 82 (79 to 86) |
| Thames Valley | 1991–2012 | 398 | 1.2 (1.1 to 1.4) | 82 (79 to 86) |
| North West Thames | 1991–2004 | 826 | 1.2 (1.2 to 1.3) | 83 (80 to 86) |
| East Midlands and South Yorkshire | 1998–2012 | 1156 | 1.2 (1.1 to 1.2) | 77 (74 to 79) |
| Merseyside and Cheshire | 1995–1999 | 183 | 1.3 (1.1 to 1.5) | 82 (76 to 87) |
| Wessex | 1994–2012 | 668 | 1.3 (1.2 to 1.4) | 86 (84 to 89) |
| Northern England | 2000–2012 | 603 | 1.4 (1.3 to 1.6) | 79 (76 to 83) |
| Wales | 1998–2012 | 772 | 1.5 (1.4 to 1.6) | 82 (80 to 85) |
| Total | 1.3 (1.2 to 1.3) | 81 (80 to 82) |
EUROCAT, European Surveillance of Congenital Anomalies; NTD, neural tube defect.