NICE recommendations for management of RE/PS (rolandic epilepsy/Panayiotopoulos Syndrome)
| NICE recommendations for rolandic epilepsy (BECTS)/Panayiotopoulos Syndrome ▸ Diagnosis and investigation by paediatrician with expertise ▸ Investigation to include EEG confirmation of electroclinical syndrome ▸ Neuroimaging not usually indicated in BECTS ▸ ‘Children, young people and adults with epilepsy should be given information about their seizure type(s) and epilepsy syndrome, and the likely prognosis.’ ▸ ‘Discuss with the child or young person, and their family and/or carers, whether AED treatment for BECTS spikes, Panayiotopoulos syndrome…is indicated.’ ▸ ‘Be aware that carbamazepine and oxcarbazepine may exacerbate or unmask continuous spike and wave during slow sleep, which may occur in some children with RE/BECTS.’ |
| First-line AEDs | Adjunctive AEDs | Other AEDs considered in tertiary care |
|---|---|---|
| Carbamazepine Lamotrigine Levetiracetam Oxcarbazepine Sodium valproate | Carbamazepine Clobazam Gabapentin Lamotrigine Levetiracetam Oxcarbazepine Sodium valproate Topiramate | Eslicarbazepine acetate Lacosamide Phenobarbital Phenytoin Pregabalin Tiagabine Vigabatrin Zonisamide |
AEDs, antiepileptic drugs; BECTS, Benign Epilepsy with CentroTemporal Spikes; NICE, National Institute of Health and Care Excellence.