Solid colour indicates under-transmission of the rs1329650 risk allele (C*). Striped colour indicates over-transmission of the risk allele. Higher T scores on the DISC, Conners’-parents and Conners’-teachers, and each of the CBCL dimensional scores indicate worse behaviour. When risk alleles are over-transmitted (striped boxes) to the higher scores (positive Z statistic), children with this genotype have a more severe clinical presentation.
ADHD, attention-deficit hyperactivity disorder; CBCL, Child Behavioural Checklist; DISC, Diagnostic Interview Schedule for Children; SNP, single nucleotide polymorphism.