FBAT analysis of genes increasing the risk for smoking behaviours in children with ADHD
| Marker (chromosome) | rs number | Alleles | Allele frequency | No. of informative families | Z statistic | p Value | Effect size |
|---|---|---|---|---|---|---|---|
| CHRNA3 (15q25) | rs1051730 | C | 0.661 | 160 | 1.52 | 0.13 | 0.12 |
| T | 0.339 | 160 | −1.52 | 0.13 | 0.12 | ||
| LOC100188947 (10q25) | rs1028936 | A | 0.827 | 108 | 1.44 | 0.15 | 0.14 |
| C | 0.173 | 108 | −1.44 | 0.15 | 0.14 | ||
| LOC100188947 (10q25) | rs1329650 | A | 0.252 | 141 | −2.30 | 0.02 | 0.19 |
| C | 0.748 | 141 | 2.30 | 0.02 | 0.19 | ||
| Near DBH (9) | rs3025343 | A | 0.109 | 83 | 0.37 | 0.72 | 0.04 |
| G | 0.891 | 83 | −0.37 | 0.72 | 0.04 | ||
| BDNF (11p13) | rs6265 | A | 0.184 | 119 | −0.79 | 0.43 | 0.07 |
| G | 0.816 | 119 | 0.79 | 0.43 | 0.07 |
ADHD, attention-deficit hyperactivity disorder; FBAT, family-based association tests. The only significant association observed between one of the genetic markers and overall ADHD diagnosis is highlighted in bold.