Table 2

Effect of SCQ cut-off points for identifying ASD in extremely preterm children (n=173) at 11 years of age

Number of positive screensPredictive values
SCQ cut-off scoreASD (n=11)No ASD (n=162)Sensitivity (95% CI)Specificity (95% CI)PPV (95% CI)NPV (95% CI)
≥14*102291% (59% to 99%)86% (80% to 91%)31% (16% to 50%)99% (96% to 100%)
≥1591982% (48% to 98%)88% (82% to 93%)32% (16% to 52%)99% (95% to 100%)
≥227764% (31% to 89%)96% (91% to 98%)50% (23% to 77%)99% (94% to 99%)
  • ASD, autism spectrum disorder; NPV, negative predictive value; PPV, positive predictive value; SCQ, Social Communication Questionnaire.

  • * Optimal cut-off in this population.

  • Optimal established cut-off.