Table 4

 Aetiology of true congenital hypothyroidism for period 2, before the introduction of dual scanning (pre-1999) in the West of Scotland and after the introduction of dual scanning (from January 1999)

Aetiology1994–1998Aetiology scanned1999–2003Aetiology scannedWhole cohort
’94–’98’99–’031994–2003
*Two instances of isoimmune thyroiditis and one instance of maternal radioiodine administration.
All77 (100%)23.4%84 (100%)77.4%161 (100%)
Unknown52 (67.5%)11.5%20 (23.8%)25%72 (44.7%)
Ectopia4 (5.2%)75%22 (26.2%)100%26 (16.2%)
Athyreosis5 (6.5%)60%18 (21.4%)100%23 (14.3%)
Hypoplasia1 (1.3%)100%8 (9.5%)87.5%9 (5.6%)
Dyshormonogenesis9 (11.7%)55.5%12 (14.3%)100%21 (13.0%)
Other cause*2 (2.6%)0%1 (1.2%)100%3 (1.9%)
Insufficient data4 (5.2%)3 (3.6%)66.7%7 (4.3%)