Results of 101 children with available results at 10–20 years and their combined thyroid function and antibody status at first testing
| Thyroid disease (hypothyroidism), 2nd test | ||||
|---|---|---|---|---|
| Hypothyroidism | “Normal” | Total | ||
| The children are defined at age 10–20 years as having hypothyroidism or “normal” (IR-TSH is included as “normal” meaning not having hypothyroidism, and not needing therapy). Unfortunately the antibody status of one child with hypothyroidism was unavailable. | ||||
| Sensitivity 100%; specificity 95% (95% CI 91–99%). | ||||
| Positive predictive value 17%; negative predictive value 100%. | ||||
| Likelihood ratio for positive test result 20; likelihood ratio for negative test result very small (<0.001). | ||||
| Thyroid antibody and isolated raised TSH, 1st test | Positive for both | 1 | 5 | 6 |
| Negative for one or both | 0 | 95 | 95 | |
| Total | 1 | 100 | 101 | |