Important history details suggestive of IEM
| Features to suggest an IEM | |
|---|---|
| Pregnancy | Maternal health |
| HELLP, AFLP | |
| Family history | Consanguinity |
| Unexplained neonatal or infantile deaths | |
| Three generation pedigree | |
| Past medical history of delayed child | Unexplained hypoglycaemia |
| Encephalopathy | |
| Protein aversion | |
| Self-injurious behaviour | |
| Psychiatric symptoms | |
| Seizure disorder | |
| Type of developmental delay | Regression |
| Hypotonia | |
| Speech delay |