Definition of components of the IRS11
| IRS component | Definition |
|---|---|
| 1. Obesity | BMI ⩾95th centile for age and sex |
| 2. Abnormal glucose homoeostasis | Any of the following: |
| A. Fasting hyperinsulinaemia | |
| B. Impaired fasting glucose (⩾6.1 mM/l) | |
| C. Impaired glucose tolerance: glucose at 120 min ⩾7.8 mM/l | |
| 3. Hypertension | Systolic blood pressure ⩾95th centile for age and sex |
| 4. Dyslipidaemia | Any of the following: |
| A. High triglycerides (⩾1.75 mM/l) | |
| B. Low HDL (<0.9 mM/l) | |
| C. High total cholesterol (⩾95th centile) |