Serogroup distribution of S pneumoniae among isolates from children with IPD in each decade, according to the serogroups present in the pneumococcal conjugate vaccines
| Serogroups included in the pneumococcal conjugate vaccines | Number of isolates (%) | |||
|---|---|---|---|---|
| 1980–89 | 1990–99 | |||
| (n = 91) | (n = 135) | |||
| 7-valent pneumococcal conjugate vaccine, PCV7 | ||||
| 14 | 16 | (18) | 34 | (25) |
| 6 | 7 | (8) | 22 | (16) |
| 19 | 13 | (14) | 15 | (11) |
| 23 | 9 | (10) | 10 | (8) |
| 18 | 7 | (8) | 9 | (7) |
| 4 | 4 | (4) | 7 | (5) |
| 9 | 3 | (3) | 4 | (3) |
| Subtotal | 59 | (65) | 101 | (75) |
| 9-valent vaccine, PCV9 = PCV7 + the following serogroups | ||||
| 1 | 9 | (10) | 13 | (10) |
| 5 | 1 | (1) | 2 | (1) |
| Subtotal | 10 | (11) | 15 | (11) |
| 11-valent vaccine, PCV11 = PCV9 + the following serogroups | ||||
| 3 | 4 | (4) | 4 | (3) |
| 7 | 9 | (10) | 1 | (1) |
| Subtotal: | 13 | (14) | 5 | (4) |
| Non-vaccine serogroups | 9 | (10) | 14 | (10) |
| Total | 91 | (100) | 135 | (100) |