Ion channelopathies causing arrhythmias in children
| Ion channel | Syndrome | Gene defect | Arrhythmia |
|---|---|---|---|
| Na+ | Brugada | SCN5a | Ventricular fibrillation |
| Sudden death | |||
| Na+ | Long QT 3 | SCN5a | Torsade de Pointes |
| Sudden death | |||
| K+ | Short QT syndrome | KCNH2 | Atrial arrhythmias |
| Long QT 1 | KCNE1 | Torsades de Pointes | |
| Long QT 2 | HERG | ||
| Ca++ | Catecholaminergic ventricular tachycardia (Coumel’s) | hRyR2 CASQZ | Bidirectional ventricular tachycardia |