Outcomes of culture confirmed tuberculosis in HIV infected children (n = 93 episodes; n = 87 patients)
| TB episodes (n = 93) | Total | HIV CDC stage B | HIV CDC stage C | p value* |
|---|---|---|---|---|
| n = 93 (%) | n = 35 (%) | n = 58 (%) | ||
| CDC HIV stage: Centers for Disease Control and Prevention.6 *χ2 statistic, one sided exact p value. **Statistically significant, Fisher’s exact test. | ||||
| Missing data for n = 93 episodes: culture negative, 36/93 (41.9%); radiological improvement, 23 (24.7%); combined bacteriological and/or radiological cure, 13/93 (14%). All other data are complete. | ||||
| Lost to follow up: lost to follow up after completion of TB therapy as measured at the end of the study period (July 2002). Total deaths: deaths during TB episode therapy and after completion of therapy until lost to follow up or at the end of study period. | ||||
| Culture negative | 44/93 (47.3) | 16/35 (45.7) | 28/58 (48.3) | 0.565 |
| n = 56 done (60.2) | n = 20 done | n = 36 done | ||
| (57.1) | (62.1) | |||
| Radiological improvement | 30/93 (32.2) | 9/35 (25.7) | 21/58 (36.2) | 0.824 |
| n = 70 done | n = 22 done | n = 48 done | ||
| (75.3) | (62.9) | (82.8) | ||
| Bacteriological and/or radiological cure | 54/93(58.1) | 19/35 (54.3) | 35/58 (60.3) | 0.583 |
| n = 80 done | n = 28 done | n = 52 done | ||
| (86.0) | (80.0) | (89.7) | ||
| Severe PEM at therapy completion | 12/93 (12.9) | 1/35 (2.9) | 11/58 (19.0) | 0.021** |
| TB patients (n = 87) | n = 87 (%) | n = 32 (%) | n = 55 (%) | |
| Death on TB therapy | 18 (20.7) | 4 (12.5) | 14 (25.5) | 0.107 |
| Total deaths | 34 (39.1) | 10 (31.3) | 24 (43.6) | 0.181 |
| Lost to follow up | 13 (14.9) | 6 (18.8) | 7 (12.7) | 0.322 |
| Further confirmed TB episode | 6 (6.9) | 3 (9.4) | 3 (5.5) | 0.405 |