Allergic rhinitis in children with otitis media
| Citation | Study group | Study type (level of evidence) | Outcome | Key results | Comments |
|---|---|---|---|---|---|
| Caffarelli et al (1998) | 172 children with OME referred because of symptoms to the Centre for the Study of OME. 200 healthy children as controls | Case-control study (level 2b) | Prevalence of allergic rhinitis | 16.3% in children with OME; 5.5% in controls. OR = 3.34 (95%CI 1.6 to 6.3), p<0.001 | Well defined and rigorous diagnostic criteria of OME and AR. Presence of an adequate random control population. Sufficient sample size |
| Kayhan et al (2002) | 22 children with OME; 21 children with no symptoms of otolaryngological disease as controls | Case-control study (level 2b) | Prevalence of allergic rhinitis | 23% in children with OME; 4.8% in controls. OR = 5.9 (95% CI 0.6 to 55.4), p>0.05 | Good quality of definition of diagnosis of OME and AR. Small numbers. Article in Turkish |
| Alles et al (2001) | 209 children with OME | Case series (level 4) | Prevalence of atopy and allergic disease (rhinitis, asthma, eczema) | Prevalence of AR = 89% | Poor quality of definition of diagnosis of OME and AR. Lack of a control population |
| Ogawa (2002) | 185 children with OME | Case series (level 4) | Description of various outcomes (allergic and non-allergic) | Prevalence of AR = 14% | Unknown quality of definition of diagnosis of OME and AR. Lack of a control population. Article in Japanese |