Table 1

DHA as weight% of total fatty acids in plasma TL, TG, PL, and CE, and erythrocyte lipids, PC, and PE followed by latencies (ms) of P100 wave

BaselineEnd of supplementation3 years after the end of supplementation
VariableUnsupplementedSupplementedUnsupplementedSupplementedUnsupplementedSupplemented
Data are expressed as mean±SD (median; min–max).
LCPUFA supplemented v unsupplemented: p<0.05 for DHA in plasma TL, PL, CE, EryPC, EryPE, pattern reversal VEPs at 15′, and flash VEPs at 2Hz-1J at the end of the supplementation period.
Different superscripts (a, b, c) indicate significant within group differences between time points.
Plasma TL DHA1.2±0.4 (1.2; 0.5–2.0)1.1±0.3 (1.0; 0.7–1.8)a1.1±0.3 (1.1; 0.8–2.0)2.3±1.1 (1.7; 1.2–3.9)b1.0±0.2 (1.0; 0.5–1.4)1.0±0.2 (1.0; 0.7–1.4)a
Plasma PL DHA1.7±0.5 (2.0; 0.8–2.3)1.6±0.3 (1.6; 1.1–2.1)a1.6±0.4 (1.4; 0.9–2.5)3.1±1.6 (2.2; 1.5–6.1)b1.4±0.4 (1.4; 0.7–2.0)1.3±0.3 (1.5; 0.9–2.0)a
Plasma TG DHA0.1±0.1 (0.1; 0.0–0.3)0.2±0.2 (0.1; 0.0–0.1)a0.3±0.3 (0.1; 0.1–1.1)0.6±0.5 (0.3; 0.1–1.5)b0.2±0.1 (0.1; 0.0–0.4)0.2±0.1 (0.2; 0.1–0.5)a
Plasma CE DHA0.2±0.1 (0.2; 0.1–0.6)0.2±0.0 (0.2; 0.1–0.4)a0.2±0.1 (0.2; 0.1–0.6)0.5±0.2 (0.3; 0.2–0.9)b0.2±0.1 (0.2; 0.0–0.5)0.1±0.1 (0.2; 0.0–0.3)a
Ery DHA1.1±0.5 (0.9; 0.5–2.4)1.3±0.6 (1.1; 0.5–2.3)a1.5±0.5 (1.6; 0.8–2.5)2.8±1.5 (2.0; 1.2–5.1)b1.3±0.6 (1.3; 0.6–2.5)1.6±0.7 (1.2; 0.9–3.1)c
EryPC DHA0.3±0.1 (0.3; 0.1–0.7)0.4±0.1 (0.3; 0.1–0.6)a0.3±0.2 (0.3; 0.1–0.7)0.8±0.2 (0.8; 0.5–1.3)b0.6±0.8 (0.2; 0.1–3.0)0.4±0.2 (0.3; 0.2–1.0)a
EryPE DHA1.8±0.7 (1.9; 0.5–2.7)2.2±1.0 (2.1; 0.3–3.7)a1.3±0.9 (1.1; 0.3–2.2)3.7±1.7 (3.5; 1.5–6.1)b1.8±0.9 (1.5; 0.6–3.5)2.1±0.8 (2.0; 1.1–3.9)a
Pattern reversal VEP
    60′109±6 (111; 99–119)106±3 (108; 106–112)109±8 (108; 96–125)104±4 (102; 100–112)106±5 (106; 97–113)101±3 (101; 95–106)
    15′116±8 (115; 100–133)113±8 (115; 96–128)a118±11(115; 101–132)107±6 (108; 98–115)b110±7 (110; 100–122)108±5 (107; 102–122)
Flash VEP
    1Hz-2J123±8 (124;112–136)a122±9 (121; 111–142)a114±8 (111; 104–130)113±10 (112; 100–128)107±10 (107; 94–123)b104±10 (106; 80–115)b
    2Hz-1J124±11 (121; 105–142)a121±11 (120; 104–138)a121±8 (118; 110–138)111±12 (109; 97–131)b111±10 (111; 94–122)b114±5 (116; 104–126)