Table 2
CitationStudy groupStudy type (level of evidence)OutcomeKey resultsComments
Deviet al (1997) 47 children in ED with severe status asthmaticusRCT (level 1b)Admission to hospitalARR 0.34 (95% CI 0.07 to 0.61); NNT 3 (95% CI 2 to 14)0.2 cc/kg 50% MgSO4 given
Scarfone et al (2000) 54 children in ED with moderate status asthmaticusRCT (level 1b)Admission to hospitalARR 0.07 (95% CI −0.2 to 0.34), NNT 14 (95% CI 3 to 8: NNH 8 to 5)75 mg/kg MgSO4 (max 2.5 g)
Ciarallo et al (1996) 31 children in ED with moderate to severe status asthmaticusRCT (level 1b)Admission to hospitalARR 0.27 (95% CI 0.05 to 0.49), NNT 4 (95% CI 2 to 19)25 mg/kg MgSO4 (max 2 g)
Ciarallo et al (2000) 30 children in ED with moderate to severe status asthmaticusRCT (level 1b)Admission to hospitalARR 0.5 (95% CI 0.24 to 0.76), NNT 2 (95% CI 1 to 4)40 mg/kg MgSO4 (max 2 g)