Table 1

Health outcome estimates

Parameters	All	0–4	5–14	15–44	45–64	65+	Source*
*Reference numbers in square brackets.
VZIG, varicella zoster immune globulin; PHN, post-herpetic neuralgia.
% cases consult GP
Natural varicella		45%	45%	72%	82%	100%	[12]
Breakthrough varicella		45%	45%	72%	82%	100%	[12,13]
Zoster		100%	100%	100%	100%	100%	[12]
Number of visits per consultation
Natural varicella		1.18	1.24	1.29	1.40	1.43	[12]
Breakthrough varicella		1.00	1.00	1.00	1.00	1.00	Assumption
Zoster		1.07	1.18	1.36	1.43	1.68	[12]
Hospitalisations per case
Natural varicella		0.37%	0.14%	0.62%	1.38%	3.14%	[12]
Breakthrough varicella		0.07%	0.03%	0.12%	0.28%	0.63%	[12,14]
Zoster		1.12%	0.66%	0.50%	0.60%	2.28%	[12]
Length of stay
Natural varicella		2.22	2.96	3.97	5.77	10.57	[12]
Breakthrough varicella		2.22	2.96	3.97	5.77	10.57	[12]
Zoster		3.53	3.35	4.58	5.23	13.54	[12]
Case fatality
Natural varicella		0.001%	0.001%	0.009%	0.073%	0.689%	[12]
Zoster		0.000%	0.001%	0.002%	0.002%	0.061%	[12]
VZIG per case		0.2%	0.2%	3.3%	0.2%	0.2%	PHLS
PHN per zoster case		0%	1%	4%	11%	31%	[17]
Duration of PHN (days)	511						[17]
QALY lost per case
Natural varicella		0.004	0.004	0.005	0.005	0.005	See methods
Breakthrough varicella		0.001	0.001	0.001	0.001	0.001	Assumption
Zoster	0.010						[17]
PHN	0.462						[17]