Difference in percentage change in haemodynamics during crossover with MDI versus SVN
| Time (h) | HR | p | SBP | p | DBP | p |
|---|---|---|---|---|---|---|
| Statistically significant (p<0.05) percentage changes in haemodynamics with each method of administration at each sample time determined by paired t test. Values represent means (SEM). | ||||||
| HR, heart rate (beats per minute); SBP, systolic blood pressure (mm Hg); DBP, diastolic blood pressure (mm Hg); MDI, metered dose inhaler plus spacer; SVN, small volume nebuliser. | ||||||
| 0.5 | −3.3 (5.6) | 0.59 | 8.4 (11.8) | 0.53 | 5.5 (11.0) | 0.64 |
| 1 | 3.1 (2.8) | 0.32 | −2.2 (10.3) | 0.84 | −4.8 (12.9) | 0.72 |
| 2 | 10.1 (5.7) | 0.13 | −4.5 (8.2) | 0.60 | −0.9 (9.5) | 0.93 |
| 4 | 6.5 (8.5) | 0.47 | 9.9 (16.6) | 0.58 | 12.5 (20.4) | 0.56 |