DS and SH n = 16 | Control group with DS n = 25 | |
---|---|---|
No differences between the two groups were statistically significant. | ||
DS, Down’s syndrome; SH, subclinical hypothyroidism; FS, fractional shortening; VCFc, rate corrected velocity of circumferential fibre shortening; σes, end-systolic meridional wall stress; SVI, stress velocity index; DT, deceleration time; IVRT, isovolumic relaxation time. | ||
Systolic function | ||
FS (%) | 40 (3.8) | 39.3 (4.5) |
VCFc (circ/sec) | 1.35 (0.3) | 1.31 (0.3) |
σes (g/cm2) | 32 (13) | 30.7 (6.3) |
SVI Z score | 0.78 (0.34) | 0.34 (0.11) |
Diastolic function | ||
Mitral peak E (m/s) | 1 (0.1) | 1.1 (0.2) |
Mitral peak A (m/s) | 0.6 (0.1) | 0.7 (0.1) |
E/A ratio | 1.66 (0.2) | 1.42 (0.2) |
DT (ms) | 102.8 (22) | 107.5 (30) |
IVRT (ms) | 51.6 (8.4) | 53.6 (8.1) |
Mitral annulus peak Ea (m/s) | 0.19 (0.03) | 0.20 (0.03) |
Mitral annulus peak Aa (m/s) | 0.14 (0.04) | 0.12 (0.04) |
E/Ea | 5.26 (0.8) | 5.5 (1.27) |