Table 3

Adjusted odds ratios (95% CI)* for a high hygiene score according to perinatal, maternal, social, and environmental factors adjusted within and between groups

Within groupBetween groups
GroupAdjusted OR (95% CI)pAdjusted OR (95% CI)p
*Adjusted OR (95% CI) are calculated comparing the top quintile of hygiene score versus the bottom 4 quintiles.
Perinatal factors
Maternal parity
    010.0004NS
    11.11 (0.9 to 1.2)
    2+1.3 (1.15 to 1.5)
Duration of breast feeding
    Never10.0002NS
    <1 month0.9 (0.7 to 1.02)
    1–3 months0.9 (0.7 to 1.03)
    3–6 months0.8 (0.7 to 0.9)
    >6 months0.7 (0.6 to 0.8)
Maternal factors
Maternal smoking during pregnancy
    None1<0.00011<0.0001
    1–9 per day1.25 (1.03 to 1.51)1.34 (1.09 to 1.66)
    10–19 per day1.63 (1.37 to 1.94)1.77 (1.44 to 2.18)
    20+ per day1.97 (1.51 to 2.57)2.18 (1.6 to 2.98)
Maternal highest educational qualification
    CSE1.61 (1.32 to 1.97)<0.00011.3 (1.01 to 1.6)0.0003
    Vocational1.23 (0.9 to 1.53)1.02 (0.8 to 1.3)
    O level1.24 (1.04 to 1.5)1.02 (0.8 to 1.2)
    A level1.54 (1.28 to 1.83)1.3 (1.1 to 1.6)
    Degree11
Childcare by childminder/nursery (>10 hours per week)
    No1<0.00011<0.0001
    Yes0.67 (0.58 to 0.78)0.72 (0.62 to 0.85)
Maternal eczema
    No10.000710.004
    Yes0.81 (0.71 to 0.91)0.83 (0.73 to 0.94)
Social factors
Housing tenure
    Local authority housing1.68 (1.44 to 1.97)<0.00011.36 (1.14 to 1.62)0.003
    Private rented1.10 (0.91 to 1.32)1.01 (0.83 to 1.23)
    Mortgaged/owned11
Damp housing (8 months)
    No10.000410.001
    Yes0.82 (0.74 to 0.92)0.8 (0.7 to 0.9)
Environmental factors
Weekly contact with pets
    Non-furry pets (v none)1.2 (1.01 to 1.4)0.031.2 (1.02 to 1.4)0.03
Chemical exposure score:
    At 8 months1.07 (1.06 to 1.08)<0.00011.07 (1.06 to 1.08)<0.0001
Month of questionnaire return (for hygiene score @ 15 months)
    October–March (winter)0.64 (0.58 to 0.71)0.63 (0.6 to 0.7)<0.0001
    April–September (summer)1<0.00011