Table 6

Association between determinants and poor Full Scale Intelligence Quotient (IQfs <−1 SD), poor Verbal Intelligence Quotient (IQv <−1 SD), and poor Performal Intelligence Quotient (IQp <−1 SD): multivariate logistic regression model

Intelligence scoreLow IQfs†# OR† (95% CI)¶Low IQv† OR† (95% CI)¶Low IQp† OR† (95% CI)¶
*p<0.05; **p<0.01; †low IQfs, low IQv, and low IQp = <−1 SD; †OR = adjusted odds ratio; ¶95% CI, 95% confidence interval; ‡use of aluminium containing phosphate binders; §RRT, renal replacement therapy; #Hosmer and Lemeshow Goodness of fit test IQfs: p=0.82, IQp: p=0.77, IQv: p=0.96.
NOTE: only significant determinants of the univariate analysis were entered in the model and only significant determinants in the multivariate model are shown (all set at p<0.4).
Duration of RRT§ ≥18 y v <18 y1.2 (0.2 to 9.2)1.0 (0.2 to 7.0)
Duration of dialysis ≥4.0 y v <4.0 y3.0 (1.3 to 6.6)**3.6 (1.4 to 9.1)**2.1 (1.0 to 4.6)*
Duration of anaemia ≥1.5 y v <1.5 y1.4 (0.6 to 3.2)1.5 (0.7 to 3.4)1.5 (0.7 to 3.2)
Aluminium exposure‡: yes v no0.6 (0.2 to 1.8)0.8 (0.3 to 2.3)
RRT§ at investigation: dialysis v renal graft0.3 (0.1 to 0.8)*
RRT onset 1972–1982 v 1982–19921.7 (0.2 to 11.7)
Primary disease: SLE/cystinosis v other>10 (0 to ∝)>10 (0 to ∝)>10 (0 to ∝)