Comparison of clinical features in children with DS and non-DS patients
| Clinical feature | Total | DS (%) | Non-DS (%) | p value |
| Total | 3651 | 55 | 3596 | |
| Sex | ||||
| Male | 2081 | 33 (60) | 2048 (57) | |
| Female | 1570 | 22 (40) | 1548 (43) | NS |
| Age (y) | ||||
| 0–1 | 314 | 2 (4) | 312 (9) | |
| 2–9 | 2805 | 51 (93) | 2754 (77) | |
| 10+ | 532 | 2 (4) | 530 (15) | 0.05 |
| WBC (× 109 /l) | ||||
| <20 | 2272 | 33 (60) | 2239 (62) | |
| 20–49 | 591 | 9 (16) | 582 (16) | |
| 50–99 | 335 | 10 (18) | 325 (9) | |
| ⩾100 | 453 | 3 (5) | 450 (13) | NS |
| CNS involvement | ||||
| Yes | 59 | 1 (2) | 58 (2) | |
| No | 3592 | 54 (98) | 3538 (98) | NS |
| Immunophenotype | ||||
| T-ALL | 343 | 0 (0) | 343 (10) | |
| C/pre-B | 2941 | 48 (87) | 2893 (80) | |
| Null | 124 | 0 (0) | 124 (3) | 0.012-150 |
↵2-150 T-ALL v Null/C/pre-B.