Table 1

Serum concentrations of total homocysteine, folate, and vitamin B12 in renal transplant recipients

MTHFR C677T gene polymorphism Before folate treatment After folate treatment p value
Homocysteine (μmol/l)
CC16.3  (7.7)9.7  (3.3)<0.01
CT20.1 (18.4)10.3 (3.3)<0.05
TT19.6 (11.7)10.8 (4.4)NS
Folate (ng/ml)
CC8.2 (4.3)17 (3.6)<0.01
CT5.3 (4.8)16.4 (4.8)<0.01
TT7.8 (3.2)15 (4.9)<0.05
Vitamin B12(pg/ml)
CC388 (187)402 (202)NS
CT285 (175)323 (191)NS
TT283 (107)358 (129)NS
  • Data are presented as mean (SD).

  • NS, non-significant.