Phenotype | Age of onset | Estimated relative frequency |
---|---|---|
Adapted from Moser et al.1 | ||
Childhood cerebral | 3–10 years | 31–35% |
Adolescent | 11–21 years | 4–7% |
Adrenomyeloneuropathy | 19–37 years | 40–46% |
Adult cerebral | Adulthood | 2–5% |
Olivopontocerebellar | Adolescence or adulthood | 1–2% |
Addison's only | Common before 7.5 years | Varies with age; up to 50% in childhood |
Asymptomatic | Biochemical abnormality only | Diminishes with age |
Common <4 years | ||
Very rare >40 years |