Clinical data
| Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | |
|---|---|---|---|---|---|
| Age at onset (year) | 8 | 14 | 8 | 2 | 8 |
| Sex | F | M | M | F | M |
| Pre-existing condition | Idiopathic marrow aplasia transplanted | Lymphatic leukaemia B | − | − | Bronchopulmonary dysplasia |
| Meningitis relapse | Asthma | ||||
| Antecedent | Sepsis | Sepsis | Status epilepticus | Fulminant hepatitis | Status asthmaticus |
| Infection | + | + | + | + | + |
| Circulatory failure | + | + | + | + | − |
| Respiratory failure | + | + | + | + | + |
| Liver failure | − | − | + | + | − |
| Renal failure | + | − | + | + | − |
| Disseminated intravascular coagulopathy | + | + | − | + | + |
| Encephalopathy | + | − | + | + | − |
| Neuromuscular signs | Quadriplegia | Flaccid quadriplegia | Diffuse muscle atrophy | Flaccid quadriplegia | Flaccid quadriplegia |
| Ventilatory dependence | Ventilatory dependence | Ventilatory dependence | |||
| Timing (days) | 12 | 15 | 18 | 8 | 9 |
| Ventilatory support (days) | 15 | 180 | 40 | 55 | 20 |
| Period spent in ICU (days) | 31 | 180 | 40 | 61 | 40 |
| Outcome | Recovery | Sequelae, death | Death | Recovery | Recovery |
| (2 months) | (3 years) | (40 days) | (6 months) | (15 days) |