Citation
|
Study group
|
Study type (level of evidence)
|
Outcome
|
Key results
|
Comments
|
Gassmaier and Weston (1999) | 20 preterm babies (mean body wt 690 g), hypotensive in spite of volume support and inotropes | Randomised, double blind, placebo controlled trial (1b) | Discontinuation of adrenaline at 12 hours | Absolute risk reduction (ARR) for withdrawal of adrenaline was 52% and NNT = 2 (95% CI 1 to 8) | All blood pressure readings measured invasively |
Bourchier and Weston (1997) | 40 hypotensive preterm babies | Randomised, open trial of hydrocortisone v dopamine (1b) | Hypotension despite treatment: dopamine: 0/19; hydrocortisone: 4/21 | Absolute risk increase (ARI) was 20% for hydrocortisone and NNH = 5 (95% CI 3 to 45) | Method of BP measurement not stated in this paper |