Table 3

Medically significant adverse drug reactions

Age	Suspected drug	Reaction
3 mth	DTP Hib and polio	Depressed level of consciousness
8 y	Fluticasone^3-150	Adrenal suppression
7 y	Fluticasone^3-150	Adrenal suppression
2 y	Interferon alfa	Motor development impaired
1 y	Diamorphine	Stevens–Johnson syndrome
1 wk	Baclofen	Neonatal convulsion
11 y	Vigabatrin^3-150	Visual disturbance
11 mth		Bupivacaine	Supraventricular tachycardia
11 mth		Bupivacaine	Ventricular fibrillation
11 y	Cephradine	Anaphylactic reaction
9 y		Carbamazepine	Hypovolaemia
9 y		Carbamazepine	Renal failure, acute
8 y	Cyclosporin	Colitis
4 mth	DTP vaccine	Convulsions
13 y	Fluticasone nasal spray^3-150	Benign intracranial hypertension
6 y	Diclofenac	Haematemesis
15 y	Lansoprazole	Neutropenia
4 y		Fluticasone^3-150	Adrenal suppression
4 y		Fluticasone^3-150	Hypoglycaemic convulsion
4 mth	DTP Hib	Convulsions
1 day		Atracurium	Acute circulatory failure
			Apnoea
			Convulsions
			Disseminated intravascular coagulation
			Hypoglycaemia
			Metabolic acidosis

↵3-150 Reports for these drugs were specifically requested in monthly reminder letters.