Genes implicated in idiopathic epilepsies
| Epilepsy syndrome | Inheritance | Gene location | Gene | References |
|---|---|---|---|---|
| Mendelian inheritance | ||||
| Benign familial neonatal convulsions | AD | 20q (EBN1) | KCNQ2 | 4, 5 |
| 8q24 (EBN2) | KCNQ3 | 6, 7 | ||
| Benign familial infantile convulsions | AD | 19q | Unknown | 8 |
| Autosomal dominant nocturnal frontal lobe epilepsy | AD | 20q13.2 | CHRNA4 | 9, 10, 11 |
| Generalised epilepsy with febrile seizures plus | AD | 19q13 | SCN1B | 12 |
| 2 | Unknown | 13 | ||
| Non-mendelian inheritance | ||||
| Juvenile myoclonic epilepsy | Complex | 15q14 | ?CHRNA7 | 14 |
| 6p (EJM1) | Unknown | 15, 16 | ||
| Childhood absence epilepsy (and/or EEG trait) | Complex | 8q24 | Unknown | 17 |
| Juvenile absence epilepsy | Complex | ?21q22.1 | ?GRIK1 | 18 |
| Benign epilepsy with centrotemporal spikes | Complex | 15q14 | Unknown | 19 |
EEG, electroencephalogram.