Table 5

Five year actuarial percentage survival rates (SE) by calandar period of diagnosis, with results of χ2 test for trend in survival with calendar period

1980–841985–891990–94p Value
Age at diagnosis (years)
 029  (6.6)32  (6.1)50  (6.5)0.12
 1–475 (1.6)82 (1.3)86 (1.2)< 0.0001
 5–968 (2.2)74 (2.1)80 (1.8)< 0.0001
 10–1454 (2.8)58 (3.1)74 (2.8)< 0.0001
Sex
 Male65 (1.6)71 (1.5)80 (1.3)< 0.0001
 Female70 (1.7)77 (1.6)83 (1.4)< 0.0001
White blood cell count (× 109/l)
 0–4974 (1.3)79 (1.2)86 (1.0)< 0.0001
 50+44 (2.7)56 (2.6)68 (2.3)< 0.0001
Immunophenotype
 Common (incl. pre-B)74 (1.4)80 (1.1)86 (1.0)< 0.0001
 T cell41 (3.5)50 (3.9)62 (3.4)< 0.0001
 B cell (mature)33 (10.3)45 (11.1)68 (8.4)0.0054
 Null48 (5.5)56 (5.4)65 (5.5)0.022
Down’s syndrome
 Yes42 (10.1)46 (10.6)78 (7.3)0.022
 No68 (1.2)74 (1.1)81 (1.0)< 0.0001