Case control difference scores on selected measures of cognitive and academic function by creatinine severity group5-150
| Assessment | Severity group 1 | Severity group 2 | Severity group 3 | p Value5-151 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | HUS5-152 | Control5-152 | Difference5-153 | n | HUS | Control | Difference | n | HUS | Control | Difference | ||||
| Wechsler | |||||||||||||||
| Verbal IQ | 27 | 101.7 | 104.8 | −2.6 (3.4) | 31 | 108.8 | 103.4 | −0.4 (3.4) | 33 | 100.8 | 107.8 | −6.0 (2.9) | 0.69 | ||
| Performance IQ | 27 | 105.5 | 103.9 | 2.3 (2.7) | 31 | 109.2 | 105.7 | 1.3 (3.4) | 33 | 101.8 | 106.8 | −5.1 (2.9) | 0.26 | ||
| Full scale IQ | 27 | 104.1 | 104.4 | 0.4 (3.0) | 31 | 110.0 | 104.6 | 0.8 (3.2) | 33 | 101.5 | 107.1 | −5.4 (2.3) | 0.37 | ||
| WIAT | |||||||||||||||
| Reading | 25 | 107.6 | 99.7 | 6.5 (4.0) | 26 | 111.4 | 103.1 | 8.0 (3.7) | 29 | 98.5 | 101.9 | −4.1 (2.6) | 0.008 | ||
| Mathematics | 25 | 101.3 | 99.8 | 2.1 (3.4) | 26 | 104.4 | 102.4 | 6.3 (5.0) | 29 | 99.3 | 101.5 | −2.6 (2.4) | 0.50 | ||
| Spelling | 25 | 103.4 | 98.1 | 4.8 (2.9) | 26 | 106.9 | 97.8 | 5.8 (3.7) | 29 | 96.3 | 102.5 | −5.5 (3.2) | 0.05 | ||
| WRMT | |||||||||||||||
| Word identification | 25 | 106.6 | 98.1 | 6.1 (4.0) | 26 | 107.2 | 99.9 | 5.8 (4.3) | 28 | 97.1 | 101.1 | −4.6 (3.7) | 0.02 | ||
| Passage composition | 25 | 101.3 | 100.1 | 0.3 (3.4) | 26 | 103.1 | 102.0 | 3.7 (3.9) | 28 | 94.5 | 98.0 | −2.7 (3.5) | 0.06 | ||
| Total reading | 24 | 105.0 | 100.1 | 4.3 (4.2) | 26 | 106.0 | 100.8 | 5.3 (4.1) | 28 | 95.5 | 100.0 | −4.2 (3.9) | 0.02 | ||
| TOWL-2 | 18 | 104.8 | 97.4 | 5.1 (5.7) | 14 | 107.7 | 91.8 | 18.1 (6.3) | 20 | 97.0 | 104.6 | −10.1 (4.2) | 0.18 | ||
| PPVT-R | 27 | 105.4 | 105.3 | 2.3 (4.6) | 31 | 111.6 | 102.1 | 5.2 (3.5) | 33 | 102.4 | 109.6 | −6.2 (2.7) | 0.34 | ||
| SBSM | 27 | 52.2 | 50.3 | 0.9 (2.0) | 31 | 54.8 | 52.9 | 3.6 (1.7) | 33 | 50.3 | 50.6 | −1.8 (1.7) | 0.29 | ||
↵5-150 Creatinine severity groups are defined in table 4.
↵5-151 Comparison of creatinine severity group mean differences between pairs using weighted linear trend analysis.
↵5-152 Values for HUS and controls are the group means.
↵5-153 Values for differences are the mean (SE) differences between paired patients with HUS and controls.
PPVT-R, Peabody picture vocabulary test–revised; SBSM, Stanford-Binet intelligence scale (4th ed) sentence memory test; TOWL-2, test of written language–2; WIAT, Weschler individual achievement tests; WRMT, Woodcock reading mastery tests.