Hospital admissions before and after diagnosis of MCAD deficiency
| Initial diagnosis | Admissions before diagnosis (excluding the admission that led to the diagnosis) | Admissions after diagnosis | |||||
|---|---|---|---|---|---|---|---|
| Coma | Lethargy/ hypoglycaemia | No admissions | Coma | Intercurrent illness/lethargy | No admission | ||
| Prospective (n = 8) | 8 | 0 | 21-150 | 6 | |||
| Symptomatic (n = 33)1-151 | 81-152 | 91-153 | 16 | 21-154 | 101-160 | 20 | |
| Total (n = 41)1-151 | 8 | 9 | 24 | 2 | 12 | 26 | |
↵1-150 Both had more than three admissions.
↵1-151 Because one patient died during the initial admission, n = 32 and n = 40, respectively, in the follow up analysis.
↵1-152 Three of these patients had more than one episode of coma. Two others had also been admitted with lethargy.
↵1-153 Six of these patients had more than one episode.
↵1-154 One of these patients had numerous admissions, most of them were more suggestive of febrile convulsions rather than MCAD related metabolic decompensation.
↵1-160 Five of these patients had more than three admissions.