Patient 1 | Patient 2 | Patient 3 | ATM7 | Hopkins’s syndrome17 | Poliomyelitis21 | |
---|---|---|---|---|---|---|
SAP | Normal | Normal | Normal | N/↓ | Normal | Normal |
MCV | Normal | ↓Lower limbs | ↓Lower limbs | ↓Severe cases | ↓Severe cases | Normal |
CMAP | ↓/− Lower limbs | ↓Lower limbs | ↓Lower limbs | ↓/− | ↓/− | ↓ |
F wave | Slightly prolonged | − | −/N | Unknown | ||
H reflex | + (Foot muscles) | L3–S1 | L5, S1, S2 severe on right | + | + | Early feature |
Denervation | Severe L3–S1 | + | + | + | + | |
Fibrillation | + | |||||
MRI findings | Hyperintensity of anterior horn cells | Hyperintensity of anterior distal cord and right posteriorly | Hyperintensity in anterior distal thoracic cord; right > left | Normal; cord swelling; hyperintensity- diffuse or localised to AHC6 | Hyperintensity of anterior horn cells16 17 | Hyperintensity of anterior horn cells10 |
↓, reduced; +, present; −, absent; AHC, anterior horn cells; CMAP, compound motor action potential; MCV, motor conduction velocity; SAP, sensory action potential; ATM, acute transverse myelitis.