Clinical response after 48 hours of empirical treatment with once daily ceftriaxone and gentamicin in 113 febrile neutropenic episodes
| Number | Days on gentamicin (median) | Days on antibiotics (median) | Antibiotics received | ||
|---|---|---|---|---|---|
| Single daily ceftriaxone and gentamicin | |||||
| Group | |||||
| A | Afebrile and culture negative | 60 | 4 | 4 | ODG, CF |
| B | Afebrile and culture positive | 17 | 7 | 7 | ODG, CF, others |
| C | Febrile and culture positive | 7 | 2 | 6 | CF and ODG then CFZ, VAN, ± Am |
| D | Febrile and culture negative | 20 | 2 | 6 | CF and ODG then CFZ, VAN, ± Am |
| Single daily gentamicin with another antibiotic | |||||
| Afebrile culture negative | 4 | 4 | 4 | ODG, CFZ | |
| Afebrile culture positive | 5 | 5 | 5 | ODG, others | |
ODG, once daily gentamicin; CF, ceftriaxone; CFZ, ceftazidime; VAN, vancomycin or teicoplanin; Am; amphotericin or ambisome; others, CFZ (2), VAN (1), flucloxacillin (2).