Table 3

Summary of serial lung function studies in 10 young children with achondroplasia

Patient/ sex		Age at study		Respiratory rate (breaths/min)		Weight (kg)		Tidal volume (ml/kg)	Lung volume (ml/kg)	Airway resistence (kPa/l.s)		Respiratory compliance (ml/kPa/kg)
Patient/ sex		Age at study		Respiratory rate (breaths/min)		Weight (kg)		Tidal volume (ml/kg)	Lung volume (ml/kg)	Inspration	Expiration	Respiratory compliance (ml/kPa/kg)
Group 1
4/M	14	42	6.5	9.0	44.2^†	13.2^†	3.6	11.0
5/M	10	493-150	8.6	7.6	16.03-150	11.5^†	5.6	9.7
	18	65^†	9.5	8.5	23.5	1.5	1.9	10.5
9/M	5	583-150	5.9	9.5	18.0	1.6	2.3	10.1
	16	58^†	7.9	9.3	29.1	1.0	1.2	11.0
12/M	16	33	9.9	10.8	26.4	1.8	2.3	15.1
	18	32	9.4	11.2	23.2	1.5	2.5	10.5
Group 2
3/M	6	663-150	5.9	6.7	16.4	2.6	4.7	7.43-150
	10	72^†	7.0	7.4	11.9^†	1.9	2.7	6.63-150
	15	573-150	7.6	9.3	21.4	2.9	2.8	10.1
	23	553-150	9.2	9.6	22.3	0.9	1.5	10.9
8/M	12	573-150	6.7	6.7	27.9	7.03-150	1.2	6.53-150
	17	573-150	7.2	9.5	34.63-150	6.53-150	2.0	6.83-150
10/M	7	50	5.7	9.8	33.93-150	4.0	2.6	10.9
	17	59^†	9.0	8.0	22.5	1.3	1.8	8.9
Group 3
1/M	13	503-150	6.2	7.4	33.73-150	14.2^†	13.5^†	3.2^†
2/F	12	–	4.1	–	26.7	14.3^†	26.5^†	8.13-150
	31	–	8.7	–	24.5	–	–	2.4^†
6/F	4	73^†	3.3	6.9	20.1	5.2	8.43-150	9.1
	6	72^†	3.8	7.3	24.3	5.7	12.7^†	7.73-150
	9	563-150	4.5	6.7	26.3	15.3^†	14.3^†	2.6^†